- Basic information
- CohesinDB ID: CDBP00421210
- Locus: chr21-45172537-45173124
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
85% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 50%,
"4_Tx": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFATC3, POU2F2, MYCN, ZFX, ZBTB48, WT1, SMAD3, FOXA1, TET2, ERG3, ERG2, PBX2, ZFHX2, ERG, YY1, RELA, KAT2B, ONECUT1, MYC, SMARCA4, GATA1, CREB1, PKNOX1, SREBF2, CTCF, RBM22, BCL11A, HNF4A, GATA2, EGR1, HSF1, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): ADARB1,COL18A1,POFUT2,PCBP3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000197381,
ENSG00000186866,
ENSG00000182871,
ENSG00000183570,
- Related loop:
chr21:29850000-29875000~~chr21:45175000-45200000,
chr21:45150000-45175000~~chr21:45250000-45275000,
chr21:45150000-45175000~~chr21:45275000-45300000,
chr21:45150000-45175000~~chr21:45425000-45450000,
chr21:45150000-45175000~~chr21:45450000-45475000,
chr21:45150000-45175000~~chr21:45725000-45750000,
chr21:45150000-45175000~~chr21:45800000-45825000,