- Basic information
- CohesinDB ID: CDBP00421212
- Locus: chr21-45175701-45177413
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Data sourse: GSE206145, GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
85% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 44%,
"4_Tx": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NFYB, TRP47, CBFA2T2, PPARG, FOXA2, MYCN, ZSCAN5D, ZNF263, CEBPA, NME2, ZFX, XBP1, SMAD3, ZBTB48, WT1, FOXA1, TET2, LEO1, HMGB1, YY1, RELA, CREBBP, JUNB, ETS1, ONECUT1, ZNF184, RUNX3, ZNF830, SP140, GRHL3, RXRA, BATF, GLYR1, MAX, ZNF143, DNMT3B, CEBPB, TEAD1, CREB1, LMO2, ESR1, PHOX2B, CTCF, RBM22, ZHX2, HES1, AR, PAX8, SOX4, E2F6, HSF1, EED, BRD4, E2F1, MAZ, AATF, SMC3, STAG1, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): ADARB1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 820
- Number of somatic mutations (non-coding): 164
- Related genes and loops