- Basic information
- CohesinDB ID: CDBP00421214
- Locus: chr21-45179638-45180462
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Data sourse: GSE67783, GSE86191, GSE105028, ENCSR153HNT, GSE38411
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Cell type: HCT-116, K-562, BCBL-1, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
85% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 47%,
"4_Tx": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, CBFA2T2, POU2F2, CHD8, TBL1X, MYCN, ZNF263, SMC1A, KDM4C, ZFX, XBP1, WT1, ZBTB48, TET2, ERG3, LEO1, ERG2, ERG, YY1, RELA, OGG1, ATF3, BMI1, RFX1, RAD21, SP140, ZIC2, GRHL3, MAF1, FOS, CDK8, RCOR1, DNMT3B, ZNF143, STAG1, OCA2, GRHL2, ZNF334, EGR2, CTCF, RBM22, RXR, EGR1, HEXIM1, HSF1, HNRNPLL, BRD4, MAZ, PTBP1
- Target gene symbol (double-evidenced CRMs): ADARB1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 105
- Number of somatic mutations (non-coding): 21
- Related genes and loops