- Basic information
- CohesinDB ID: CDBP00421218
- Locus: chr21-45192349-45192763
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Data sourse: ENCSR000BLD, GSE72082, ENCSR000BLY, GSE105028, GSE121355, GSE25021, GSE93080, ENCSR000BKV, ENCSR703TNG, GSE106870, GSE116344, ENCSR000BLS, ENCSR000ECE, ENCSR000BMY, GSE97394, ENCSR167MTG, GSE129526, ENCSR153HNT, GSE68388, GSE83726, GSE50893
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Cell type: MCF-7, GM12892, H1-hESC, HCT-116, RH4, Hep-G2, GM2610, CVB-hiPSC, GM12878, GM19240, GM12891, HUES64, HuCC-T1, SK-N-SH, K-562, GM19099, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.811
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
85% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 47%,
"4_Tx": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, POU5F1, TOP2A, POU4F2, XBP1, GTF2B, SMAD3, SRF, ERG, RELA, CREBBP, MYC, RAD21, GRHL3, HIF1A, ARNT, GABPA, APC, NRIP1, ZNF143, NCOA3, SMAD1, MLLT1, TP53, CTCF, USF1, BCL11A, EGLN2, BRD4, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): ADARB1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 20
- Number of somatic mutations (non-coding): 0
- Related genes and loops