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Basic information

CohesinDB ID: CDBP00421221

Locus: chr21-45199827-45201411

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 85% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 52%, "15_Quies": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, TRIM25, PGR, NME2, XBP1, FOXA1, LEO1, ZNF90, ATF3, RUNX3, CBFB, GLYR1, TP63, JMJD1C, KLF5, ELF1, TRIM28, LMO2, ESR1, MLL, CTCF, TCF12, BAF155, PAX8, TRIM24, CHD8, BRD1, ZSCAN5D, POU5F1, MYCN, TOP2A, RUNX1T1, ZBTB48, STAT1, ERG, MYC, GRHL3, GABPA, HNRNPH1, NR3C1, CEBPB, SRSF3, CREB1, BMPR1A, SPI1, GATA2, ZNF644, MXD3, SREBF1, FLI1, RUNX1, SMC1A, CEBPA, ZFX, TET2, TAF15, RUNX2, GATA4, ARNT, SCRT2, PIAS1, ZNF3, NCOA1, EVI1, STAT5A, RBM22, BCL11A, TCF3, SMC3, STAG1, CBFA2T2, FOXA2, AGO1, ZNF600, WT1, BCL3, KDM1A, YY1, RELA, JUNB, SP140, ZIC2, HIF1A, OTX2, GATA3, ZNF143, AGO2, NCOA3, AR, PAX3-FOXO1, ZBTB26, RNF2, HSF1, BRD4, SCRT1, MAZ, AHR

Target gene symbol (double-evidenced CRMs): TRPM2,ADARB1,TSPEAR,COL18A1,COL6A2,FAM207A,PCBP3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 55

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000142185, ENSG00000175894, ENSG00000160256, ENSG00000197381, ENSG00000182871, ENSG00000183570, ENSG00000142173,

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Deatailed information for cohesin site CDBP00421221