- Basic information
- CohesinDB ID: CDBP00421243
- Locus: chr21-45244770-45245359
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Data sourse: GSE67783, GSE86191, GSE206145, ENCSR153HNT, GSE68388
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Cell type: RPE, HCT-116, K-562, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
85% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 35%,
"15_Quies": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRIM25, PGR, CBFA2T2, POU2F2, CHD8, MYCN, ZNF263, ZFX, ZBTB48, WT1, FOXA1, TET2, SMARCC1, YY1, RELA, MYC, SP140, GRHL3, GABPA, TP63, CHD1, ZNF750, KLF5, NCOA3, CREB1, NR2F1, ESR1, MYOD1, CTCF, TCF12, SPI1, AR, REST, ZNF479, EGLN2, BRD4, MAZ, SMC3, STAG1, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): ADARB1
- Function elements
- Human SNPs: Lifetime_smoking_index
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops