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Basic information

CohesinDB ID: CDBP00421259

Locus: chr21-45339035-45339421

Data sourse: GSE206145, GSE67783

Cell type: RPE, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 83% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 45%, "14_ReprPCWk": 40%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: YBX1, TOP2A, ZNF534, ZBTB17, FOXA1, ZNF662, ZNF473, HOXB13, ZFHX2, ERG, RELA, ZNF148, ETS1, TAL1, NKX3-1, CEBPB, GFI1B, ZNF544, PIAS1, ESR1, PKNOX1, TP53, NFKB1, EGR2, SP1, BAF155, AR, GATA2, ZNF366, GLI4, FOXP1

Target gene symbol (double-evidenced CRMs): CFAP410,PFKL,TRPM2,UBE2G2,PTTG1IP,SLC19A1,COL6A2,TSPEAR,MCM3AP-AS1,LSS,SUMO3,COL18A1,FAM207A,PCBP3,ADARB1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000175894, ENSG00000184787, ENSG00000184900, ENSG00000183255, ENSG00000160256, ENSG00000197381, ENSG00000182871, ENSG00000173638, ENSG00000183570, ENSG00000142173, ENSG00000160285, ENSG00000215424,

eachgene

Deatailed information for cohesin site CDBP00421259