- Basic information
- CohesinDB ID: CDBP00421272
- Locus: chr21-45400803-45401401
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Data sourse: ENCSR000BTU, ENCSR167MTG, GSE104888, GSE67783, GSE72082, GSE86191, ENCSR000BSB, ENCSR501LQA, GSE110061, GSE129526, ENCSR000EGW, GSE138405, GSE98367, ENCSR153HNT, GSE121355, GSE68388, ENCSR199XBQ, GSE131606
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Cell type: Macrophage, Hela-Kyoto, HCT-116, Hep-G2, Ishikawa, A-549, K-562, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 43%,
"9_Het": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBX5, SOX2, HDGF, NFIC, ZNF320, BACH2, ZNF467, JMJD1C, ELF1, TRIM28, BCLAF1, SNAI2, NFE2L2, JUN, TCF12, EP300, KLF1, DPF2, TRIM24, DDX20, SMC1, ZNF280A, TEAD4, EHMT2, XRCC3, ZNF263, POU5F1, TOP2A, ZNF317, ZSCAN21, ZBTB48, MTA2, STAT1, SAP130, NBN, TBP, ERG, MIER1, MYC, SMARCA4, ARID1B, DNMT1, RAD21, FOXK2, STAT3, XRCC5, IKZF1, NFE2, LEF1, RCOR1, ZNF639, NR3C1, CEBPB, EZH2, KLF8, ARHGAP35, SPI1, KLF17, HDAC2, SMARCA5, ZNF766, ZNF554, MAFG, CBX1, CEBPA, HDAC1, SMC1A, ZNF18, ZBTB2, ZNF384, ZNF35, ZNF184, ARNT, BACH1, SNIP1, ZEB2, SMAD4, PML, ZNF558, ZNF680, PIAS1, C11orf30, SETDB1, STAT5A, MAFK, USF1, BCL11A, REST, BCOR, MLLT1, CBX3, MTA3, CREM, E2F8, MAFF, ZNF30, MEF2C, TCF7, KDM1A, ZNF510, ZNF610, ZFP36, SKIL, TAL1, MAX, ZNF143, MTA1, GATA1, SP7, TCF7L2, TP53, PKNOX1, AR, ZBTB40, ZNF324, EGR1, MYNN, NCOR1, RNF2, BRD4, JUND, MAZ, ZNF24, ZNF316
- Target gene symbol (double-evidenced CRMs): AGPAT3,COL18A1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops