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Basic information

CohesinDB ID: CDBP00421284

Locus: chr21-45562524-45563196

Data sourse: ENCSR153HNT, GSE165895

Cell type: K-562, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 84% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 31%, "13_ReprPC": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, CHD8, BRD1, SMARCA2, ZNF263, FOXA2, EZH2phosphoT487, CBX3, ZFX, CTBP1, XBP1, ZNF317, NME2, FOXA1, CBX8, SMARCC1, ERG, RELA, CREBBP, ZNF384, EHMT2, SMARCA4, GATA4, ARNT, HIF1A, ZNF429, GABPA, SMAD4, CBX2, NR3C1, TEAD3, TEAD1, TRIM28, ZNF791, EZH2, TP53, ZBTB6, ESR1, GRHL2, SETDB1, CTCF, SPI1, EP300, AR, YAP1, TRIM24, FLI1, RNF2, ZNF410, BRD4, TCF3, ZNF280A, STAG1, AHR

Target gene symbol (double-evidenced CRMs): POFUT2,ADARB1,COL6A2,PCBP3,SLC19A1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000197381, ENSG00000186866, ENSG00000173638, ENSG00000183570, ENSG00000142173,

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Deatailed information for cohesin site CDBP00421284