- Basic information
- CohesinDB ID: CDBP00421292
- Locus: chr21-45601341-45602522
-
Data sourse: GSE67783, ENCSR153HNT, GSE86191
-
Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"14_ReprPCWk": 33%,
"15_Quies": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF468, NFIA, CBX5, LCORL, MEIS2, XBP1, RBFOX2, ZFHX2, ATF3, NFIC, ZFP64, THAP1, ZNF736, TRIM28, ZNF573, ESR1, OCA2, USF2, CTCF, GATA6, E2F6, SOX6, ZNF350, GTF2F1, EED, POU2F2, CHD8, ZSCAN5D, ZNF263, MYCN, POU5F1, MTA2, ZBTB48, ZSCAN5A, STAT1, ERG2, ERG, ZNF341, ETS1, MYC, GRHL3, RXRA, STAT3, DNMT3B, SRSF3, EZH2, SPI1, ZNF786, ZNF257, ZNF182, ZNF766, RUNX1, CBX1, SIRT6, EZH2phosphoT487, SIN3A, ZFX, TET2, SMARCC1, CREBBP, NFIB, ARNT, BACH1, SOX11, SUPT5H, CHD1, KDM6B, SMAD1, ZNF3, L3MBTL2, SETDB1, RBM22, REST, AATF, SMC3, STAG1, TRP47, FOXA2, MTA3, CBX3, HDAC6, E2F8, ZNF600, WT1, HOXB13, CREB3L1, YY1, RELA, AHR, BRG1, SP140, ZFP36, MGA, MAX, ZNF449, GATA1, CBX2, NCOA3, NR2F2, NR2F1, KDM5B, ZNF334, BHLHE40, AR, HEXIM1, HSF1, BRD4, CLOCK, MAZ, ZNF316
- Target gene symbol (double-evidenced CRMs): COL6A2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000142173,
- Related loop:
chr21:29675000-29700000~~chr21:45600000-45625000,
chr21:45125000-45150000~~chr21:45575000-45600000,
chr21:45139555-45141248~~chr21:45595927-45597822,
chr21:45139756-45141227~~chr21:45595881-45597823,
chr21:45443298-45445960~~chr21:45595973-45597848,
chr21:45443387-45444597~~chr21:45595921-45597751,
chr21:45477292-45479145~~chr21:45595881-45597823,
chr21:45477348-45479204~~chr21:45595879-45597829,
chr21:45477385-45479624~~chr21:45595863-45597829,
chr21:45477564-45479060~~chr21:45595980-45597669,
chr21:45554040-45556961~~chr21:45595973-45597835,
chr21:45554054-45556956~~chr21:45595929-45597843,
chr21:45554081-45557001~~chr21:45595879-45597829,
chr21:45554102-45556956~~chr21:45595952-45597736,
chr21:45554110-45556838~~chr21:45595949-45597798,
chr21:45554116-45557239~~chr21:45595926-45597851,
chr21:45554119-45557159~~chr21:45595927-45597579,
chr21:45554143-45556979~~chr21:45595828-45597845,
chr21:45554152-45556956~~chr21:45595863-45597829,
chr21:45554175-45556950~~chr21:45596075-45597591,
chr21:45554175-45557619~~chr21:45595128-45597851,
chr21:45554177-45557278~~chr21:45595949-45597849,
chr21:45554195-45556971~~chr21:45595813-45597858,
chr21:45554202-45556971~~chr21:45595963-45597837,
chr21:45554214-45557007~~chr21:45595996-45597719,
chr21:45554223-45557030~~chr21:45596036-45597562,
chr21:45554236-45556906~~chr21:45596001-45597798,
chr21:45554237-45556867~~chr21:45595881-45597823,
chr21:45554245-45556897~~chr21:45595980-45597669,
chr21:45554248-45557000~~chr21:45595927-45597822,
chr21:45554252-45557219~~chr21:45595919-45597671,
chr21:45554265-45556926~~chr21:45595942-45597733,
chr21:45554269-45557151~~chr21:45595915-45597807,
chr21:45554270-45556959~~chr21:45595948-45597591,
chr21:45554282-45557370~~chr21:45595721-45597781,
chr21:45554287-45556968~~chr21:45596076-45597589,
chr21:45554290-45556966~~chr21:45595867-45597858,
chr21:45554297-45556971~~chr21:45595921-45597751,
chr21:45554297-45557117~~chr21:45596246-45597503,
chr21:45554301-45556971~~chr21:45595924-45597692,
chr21:45554315-45556912~~chr21:45596110-45597788,
chr21:45554317-45556991~~chr21:45596022-45597537,
chr21:45554319-45557073~~chr21:45596152-45597534,
chr21:45554322-45556956~~chr21:45595973-45597752,
chr21:45554345-45557074~~chr21:45596127-45597522,
chr21:45554350-45556959~~chr21:45595979-45597730,
chr21:45554359-45556990~~chr21:45595975-45597766,
chr21:45554407-45556897~~chr21:45595171-45597684,
chr21:45554407-45556976~~chr21:45595965-45597845,
chr21:45554441-45556961~~chr21:45595981-45597772,
chr21:45575000-45600000~~chr21:45725000-45750000,
chr21:45575000-45600000~~chr21:45800000-45825000,
chr21:45575000-45600000~~chr21:45900000-45925000,
chr21:45575000-45600000~~chr21:45925000-45950000,
chr21:45575000-45600000~~chr21:46100000-46125000,
chr21:45600000-45625000~~chr21:46100000-46125000,