- Basic information
- CohesinDB ID: CDBP00421294
- Locus: chr21-45606044-45607726
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Data sourse: GSE67783, GSE86191, GSE98367, GSE116868, GSE111913, GSE120943, ENCSR153HNT, GSE68388
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Cell type: HCT-116, Monocytes, MB157, HuCC-T1, RT-112, K-562, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 42%,
"15_Quies": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, TRIM25, ZSCAN5C, XBP1, FOXA1, SUZ12, ZFHX2, HNRNPK, ATF3, NFIC, ZBTB5, ZBTB44, PRDM1, ZNF444, CBFB, SMARCE1, TP63, ZNF467, ZNF629, MAF, KLF5, TEAD1, ETV1, NFE2L2, ESR1, OCA2, JUN, CTCF, TCF12, BAF155, ZNF695, GATA6, DPF2, RFX5, E2F1, ZNF528, ZNF280A, TEAD4, RBPJ, TFAP2C, GLIS1, NANOG, ZNF263, POU5F1, TOP2A, MYCN, BRD3, ZNF317, ZSCAN21, ZBTB48, ZBTB17, DUX4, ZNF563, SRF, DDX5, ERG2, SP4, ERG, HOXC5, ZBTB21, ASCL1, OGG1, ZNF341, ZBTB8A, MYC, SMARCA4, RAD21, GRHL3, NKX2-1, GABPA, STAT3, XRCC5, NKX3-1, ZNF398, RCOR1, ZNF667, NR3C1, ESRRA, CREB1, EZH2, JMJD6, GRHL2, EBF3, ZHX2, SPI1, KLF17, PCBP1, HDAC2, GATA2, FLI1, MXI1, HCFC1R1, MRTFB, NCOA2, RUNX1, BCL6, SIRT6, EZH2phosphoT487, NKX2-2, AFF4, ZFX, SMAD3, PCBP2, CBX8, NFXL1, ERG3, SMARCC1, CREBBP, ZNF384, CDK6, ZNF184, SP3, PBX4, DAXX, ARNT, NRF1, NCAPH2, SP2, FOS, SMARCB1, SUPT5H, ZNF484, CDK8, MED1, ZEB1, TERF1, TEAD3, MYB, PIAS1, SETDB1, SP1, TFAP2A, ARID2, REST, ASH2L, MBD2, AATF, SMC3, STAG1, CXXC4, PAX7, TRP47, AGO1, TBL1X, CREM, SS18, ZNF600, WT1, ZNF30, FOXF1, MEF2C, HOXB13, KDM1A, YY1, RELA, JUNB, AHR, BRG1, MCM3, SP140, ZFP36, ZIC2, HIF1A, GATA3, KLF15, TAL1, MAX, NRIP1, ZNF143, CBX2, NCOA3, NEUROG2, NR2F1, KDM5B, TP53, NFKB1, ZSCAN22, EGR2, MYOD1, BRD2, BHLHE40, AR, RXR, EGLN2, TFIIIC, HSF1, RNF2, BRD4, JUND, MAZ, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): COL6A2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 21
- Related genes and loops