- Basic information
- CohesinDB ID: CDBP00421317
- Locus: chr21-45702015-45702584
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Data sourse: GSE206145-GSE177045, GSE72082
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Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 67%,
"14_ReprPCWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, ZNF660, XBP1, FOXA1, SUZ12, INSM2, NFIC, ATF3, ZNF189, CDX2, ZNF629, MAF, TEAD1, TRIM28, NFE2L2, ESR1, PITX3, USF2, JUN, TCF12, CTCF, EP300, BAF155, LMO1, PAX8, SOX4, TEAD4, GTF2F1, PDX1, GLIS1, NANOG, POU2F2, MYCN, ZNF263, TOP2A, ZSCAN21, ZBTB17, ZBTB48, DUX4, ZNF317, SRF, DDX5, SP4, ERG, ZBTB21, HOXC5, ZNF585B, CHD4, ASCL1, MYC, EZH1, RAD21, GRHL3, RXRA, NKX2-1, GABPA, STAT3, NKX3-1, RCOR1, ZNF639, ARNTL, NR3C1, CEBPB, ZNF750, CREB1, EZH2, FEZF1, GRHL2, EBF3, SPI1, EHF, GATA2, FLI1, MXI1, MRTFB, ZNF554, RUNX1, SMC1A, NKX2-2, EZH2phosphoT487, SIN3A, ZFX, POU4F2, SMAD3, TWIST1, PRDM10, CREBBP, ZNF35, ZNF184, PBX4, DAXX, ARNT, ZBTB10, HMGB2, ZEB2, PBX3, SUPT5H, CDK8, FOS, MED1, ZEB1, MYB, SCRT2, PIAS1, USF1, MAFK, SP1, GSPT2, REST, ZBTB7A, POU2F3, ASH2L, ZNF605, SMC3, STAG2, STAG1, FOXA2, CHD2, SS18, ZNF600, ZNF692, MAFF, HOXB13, BCL3, KDM1A, YY1, RELA, NEUROD1, JUNB, BRCA1, ISL1, HIF1A, OTX2, GATA3, MAX, GATA1, ZNF143, HAND2, ZFP69B, KLF4, SP7, NCOA3, TP53, PKNOX1, NFKB1, MYOD1, TBX21, BHLHE40, AR, PAX3-FOXO1, EGLN2, ZNF366, BRD4, JUND, ZNF24, FOSL2
- Target gene symbol (double-evidenced CRMs): PCBP3,SLC19A1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000173638,
ENSG00000183570,
- Related loop:
chr21:45200000-45225000~~chr21:45675000-45700000,
chr21:45325000-45350000~~chr21:45675000-45700000,
chr21:45550000-45575000~~chr21:45700000-45725000,
chr21:45675000-45700000~~chr21:45800000-45825000,
chr21:45675000-45700000~~chr21:45875000-45900000,
chr21:45675000-45700000~~chr21:45900000-45925000,
chr21:45675000-45700000~~chr21:46050000-46075000,
chr21:45675000-45700000~~chr21:46100000-46125000,
chr21:45700000-45725000~~chr21:45900000-45925000,