- Basic information
- CohesinDB ID: CDBP00421319
- Locus: chr21-45706323-45706700
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Data sourse: ENCSR000EHW, GSE120943, ENCSR000EHX
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Cell type: Monocytes, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 64%,
"14_ReprPCWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SOX2, XBP1, FOXA1, NFIC, PRDM1, ZNF467, TEAD1, ZNF573, ESR1, PITX3, JUN, CTCF, TCF12, EP300, ZNF528, TEAD4, GLIS1, CHD8, POU5F1, MYCN, RUNX1T1, CTBP1, ZNF317, ZBTB48, ERG2, ERG, OGG1, ZNF341, MYC, SMARCA4, RAD21, GRHL3, STAT3, ZNF398, RCOR1, ARNTL, CREB1, EZH2, BMPR1A, EBF3, GATA2, ZNF777, FLI1, MXI1, NCOA2, CRY1, SIN3A, ZFX, ZNF534, NMYC, ERG3, TWIST1, RARA, CREBBP, NFIB, ARNT, PBX3, CHD1, SUPT5H, FOS, MED1, SREBF2, STAT5A, REST, POU2F3, TCF3, SMC3, STAG1, TRP47, RBBP5, CHD2, EBF1, WT1, KDM1A, YY1, RELA, ISL1, SP140, TCF4, ZIC2, GATA3, ZNF519, NRIP1, ZNF143, HAND2, NCOA3, TP53, ZNF334, PHOX2B, AR, MAML3, HSF1, BRD4, MAZ, TBX2
- Target gene symbol (double-evidenced CRMs): SLC19A1,PCBP3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops