- Basic information
- CohesinDB ID: CDBP00421321
- Locus: chr21-45713326-45713848
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 56%,
"14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, POU2F2, ZSCAN5D, ZNF263, MYCN, TBL1X, ZFX, XBP1, GTF2B, ZBTB48, WT1, TWIST1, KDM1A, YY1, RELA, MYC, EZH1, SP140, TCF4, HIF1A, ARNT, GRHL3, PAX5, FOS, ZNF143, RCOR1, PDX1, NCOA3, EZH2, ESR1, OCA2, PITX3, EBF3, CTCF, USF1, PAX3-FOXO1, E2F4, ZBTB26, BRD4, MAZ, SMC3, STAG1, EED
- Target gene symbol (double-evidenced CRMs): SLC19A1,PCBP3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops