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Basic information

CohesinDB ID: CDBP00421325

Locus: chr21-45727437-45727820

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 84% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 56%, "14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CHD8, MYCN, ZFX, XBP1, GTF2B, ZBTB48, WT1, TET2, ZNF19, RELA, ZIC2, HIF1A, NRIP1, CDK8, HNRNPH1, KLF4, NCOA3, EZH2, ESR1, CTCF, SPI1, AR, SMC3, BRCA1, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): ADARB1,TSPEAR,TRPM2,COL6A2,FTCD,UBE2G2,PCBP3,FAM207A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 1

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000142185, ENSG00000175894, ENSG00000184787, ENSG00000160256, ENSG00000197381, ENSG00000183570, ENSG00000142173, ENSG00000160282,

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Deatailed information for cohesin site CDBP00421325