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Basic information

CohesinDB ID: CDBP00421330

Locus: chr21-45741837-45742013

Data sourse: ENCSR703TNG, ENCSR000EHX, ENCSR000BLY

Cell type: MCF-7, SK-N-SH

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 84% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 55%, "14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TRIM25, PGR, NME2, XBP1, FOXA1, SUZ12, MLL4, ZFHX2, HNRNPK, HDGF, ZBTB5, ZNF444, ZNF273, ZSCAN4, TP63, ZNF467, MAF, TEAD1, TRIM28, BCLAF1, ESR1, OCA2, TP73, CTCF, MNT, LMO1, PAX8, ZNF410, ZNF512B, E2F1, EHMT2, TFAP2C, POU2F2, CHD8, BRD1, MYCN, ZNF263, POU5F1, TOP2A, CTBP1, ZSCAN21, DUX4, ZBTB48, SRF, DDX5, NBN, ERG2, ERG, MYC, RFX1, RAD21, GRHL3, FOXK2, GABPA, XRCC5, IKZF1, ZNF639, ARNTL, CEBPB, SRSF3, KMT2A, CREB1, EZH2, BMPR1A, GABPB1, SPI1, HDAC2, GATA2, SSRP1, FLI1, MRTFB, NCOA2, RUNX1, BCL6, SMC1A, CRY1, ZFX, POU4F2, TET2, ERG3, ZNF18, SMARCC1, CREBBP, NOTCH1, CDK6, NFIB, ARNT, TFDP1, FOS, CDK8, SCRT2, TFAP2A, PHIP, TCF3, GLIS2, STAG1, PPARG, ZNF207, FOXA2, ZNF600, GTF2B, WT1, ZBTB33, HOXB13, ZKSCAN1, YY1, RELA, TARDBP, MCM3, SP140, ZIC2, HIF1A, GATA3, TAL1, NRIP1, GATA1, ZNF143, HAND2, BCL11B, NR2F1, ZNF687, PKNOX1, TP53, ZNF334, AR, EGLN2, HSF1, BRD4, CLOCK, MAZ, TBX2, AHR

Target gene symbol (double-evidenced CRMs): TRPM2,ADARB1,COL6A2,TSPEAR,FAM207A,FTCD,UBE2G2,PCBP3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000142185, ENSG00000175894, ENSG00000184787, ENSG00000160256, ENSG00000197381, ENSG00000183570, ENSG00000142173, ENSG00000160282,

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Deatailed information for cohesin site CDBP00421330