- Basic information
- CohesinDB ID: CDBP00421336
- Locus: chr21-45756056-45756358
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Data sourse: ENCSR000BTQ, GSE72082, ENCSR000BLS, ENCSR054FKH, GSE25021
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Cell type: MCF-7, Hep-G2
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 61%,
"14_ReprPCWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SKI, NFIA, THAP11, ZNF585A, BCL6, PPARG, FOXA2, HMG20A, CEBPA, EZH2phosphoT487, PGR, SOX13, MIER2, XBP1, RBPJ, FOXA1, SAP130, RXRB, ARID3A, HNF4G, KDM1A, RELA, CREBBP, RARA, AHR, ZFP64, GATA4, GR, RAD21, RXRA, GATA3, SMAD4, GABPA, MXD4, ZNF614, XRCC5, NRIP1, NKX3-1, HMGXB4, NR2F6, NR3C1, CEBPG, TEAD3, TEAD1, NR2F2, CREB1, RCOR2, ESR1, ZNF652, EBF3, JUN, TCF12, KAT8, SP1, NIPBL, MIXL1, HNF4A, AR, SOX5, EP300, BAF155, HDAC2, GATA2, GATA6, ZNF644, DRAP1, ZGPAT, FOXP1, NFIL3, FOXA3, ZNF175, GATAD2A, TFAP2C
- Target gene symbol (double-evidenced CRMs): ADARB1,PCBP3,SLC19A1,COL6A2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000197381,
ENSG00000173638,
ENSG00000183570,
ENSG00000142173,
- Related loop:
chr21:45125000-45150000~~chr21:45750000-45775000,
chr21:45200000-45225000~~chr21:45750000-45775000,
chr21:45325000-45350000~~chr21:45750000-45775000,
chr21:45550000-45575000~~chr21:45750000-45775000,
chr21:45625000-45650000~~chr21:45750000-45775000,
chr21:45650000-45675000~~chr21:45750000-45775000,
chr21:45750000-45775000~~chr21:45875000-45900000,
chr21:45750000-45775000~~chr21:45900000-45925000,
chr21:45750000-45775000~~chr21:46100000-46125000,