- Basic information
- CohesinDB ID: CDBP00421343
- Locus: chr21-45778187-45779393
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 43%,
"9_Het": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, SMC1A, CHD8, MYCN, ZNF263, POU5F1, ZFX, ZNF534, XBP1, ZBTB48, WT1, ZSCAN5A, FOXA1, TET2, ARID3A, YY1, RELA, MYC, SP140, GRHL3, GABPA, STAT3, MAF1, TP63, FOS, ZNF143, MED1, NCOA3, EZH2, ESR1, OCA2, NCOA1, CTCF, GSPT2, AR, REST, EGR1, FLI1, HSF1, SCRT1, BRD4, CLOCK, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): PCBP3,SLC19A1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000173638,
ENSG00000183570,
- Related loop:
chr21:45125000-45150000~~chr21:45750000-45775000,
chr21:45200000-45225000~~chr21:45750000-45775000,
chr21:45325000-45350000~~chr21:45750000-45775000,
chr21:45550000-45575000~~chr21:45750000-45775000,
chr21:45550000-45575000~~chr21:45775000-45800000,
chr21:45625000-45650000~~chr21:45750000-45775000,
chr21:45650000-45675000~~chr21:45750000-45775000,
chr21:45750000-45775000~~chr21:45875000-45900000,
chr21:45750000-45775000~~chr21:45900000-45925000,
chr21:45750000-45775000~~chr21:46100000-46125000,