- Basic information
- CohesinDB ID: CDBP00421344
- Locus: chr21-45784287-45785692
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Data sourse: GSE67783, GSE86191, GSE98367, GSE111913, GSE206145, GSE206145-NatGen2015, GSE120943, ENCSR153HNT, GSE131606, GSE38411
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Cell type: RPE, Fibroblast, HCT-116, Monocytes, RT-112, K-562, BCBL-1, HSPC, Macrophage, DKO
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 70%,
"14_ReprPCWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, PGR, BRD1, FOXA2, POU5F1, EZH2phosphoT487, MYCN, MAFG, ZFX, XBP1, DUX4, ZBTB48, WT1, FOXA1, MAFF, CBX8, YY1, RELA, CREBBP, MYC, RFX1, SP140, ZNF449, DNMT3B, ARNTL, TLE3, EZH2, ESR1, C11orf30, EGR2, PHOX2B, CTCF, MAFK, HES1, GATA2, POU2F3, STAG1, ZNF316
- Target gene symbol (double-evidenced CRMs): SLC19A1,PCBP3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 30
- Number of somatic mutations (non-coding): 0
- Related genes and loops