- Basic information
- CohesinDB ID: CDBP00421347
- Locus: chr21-45788056-45788727
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Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 53%,
"14_ReprPCWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, XBP1, FOXA1, SUZ12, ATF3, MORC2, TP63, ZSCAN4, ZNF467, ESR1, OCA2, TP73, CTCF, JUN, EP300, MNT, PAX8, RFX5, TFAP2C, EED, POU2F2, CHD8, MYCN, ZNF263, ZBTB48, STAT1, ERG, USP7, MYC, GRHL3, RXRA, STAT3, DNMT3B, ARNTL, NR3C1, CREB1, EZH2, SPI1, IRF1, SSRP1, NCOA2, ETV5, PTBP1, RUNX1, SMC1A, BCL6, EZH2phosphoT487, CRY1, ZFX, POU4F2, TET2, ERG3, ARNT, ETV6, PBX3, FOS, CDK8, BCL11A, REST, TCF3, AATF, SMC3, STAG1, TRP47, NFATC1, WT1, BCL3, KDM1A, YY1, RELA, JUNB, SP140, HIF1A, MAX, NRIP1, ZNF143, GATA1, CBX2, NCOA3, NR2F1, TP53, MYOD1, AR, HSF1, NCOR1, BRD4, JUND, CLOCK, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): PCBP3,SLC19A1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops