- Basic information
- CohesinDB ID: CDBP00421349
- Locus: chr21-45791275-45792394
-
Data sourse: ENCSR000BTQ, GSE67783, GSE72082, GSE86191, GSE111913, GSE206145, ENCSR198ZYJ, ENCSR153HNT, GSE25021
-
Cell type: MCF-7, RPE, HCT-116, Neurons-H1, RT-112, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 53%,
"14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, TRP47, BCL6, CHD8, ZSCAN5D, EZH2phosphoT487, MYCN, NKX2-2, SIRT6, ZFX, NME2, SOX2, HNF1A, ZBTB48, WT1, FOXA1, TET2, ERG3, ETV5, HOXB13, PAX6, YY1, RELA, TARDBP, OGG1, ATF3, MYC, RUNX2, THAP1, HNRNPUL1, HOMEZ, SP140, ARNT, HIF1A, CBFB, MAF1, TAL1, MAFB, APC, FOS, ZNF143, IKZF1, DNMT3B, HAND2, CBX2, PDX1, SP7, ELF1, TRIM28, NCOA3, TFAP2C, NR2F1, EZH2, ZNF3, ESR1, PKNOX1, TP73, TP53, HNF1B, ZNF334, CTCF, GATA6, RXR, REST, MXD3, HEXIM1, SREBF1, HSF1, FLI1, BRD4, FOXP1, E2F1, MAZ, AATF, ZNF528, SMC3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): PCBP3,SLC19A1
- Function elements
- Human SNPs: Spatial_processing
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 4
- Related genes and loops