- Basic information
- CohesinDB ID: CDBP00421358
- Locus: chr21-45811128-45811479
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Data sourse: ENCSR000BLD, GSE72082, GSE86191, GSE110061, ENCSR054FKH, GSE68388
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Cell type: H1-hESC, HuCC-T1, HCT-116, Hep-G2
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 64%,
"14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, SOX2, NME2, XBP1, FOXA1, PBX2, ATF3, PRDM1, PAX5, ZSCAN4, MYOG, TRIM28, LMO2, ESR1, CTCF, MNT, IRF4, SOX6, ZNF528, ZNF175, GLIS1, NANOG, CHD8, ZNF263, MYCN, RUNX1T1, POU5F1, ZBTB48, DUX4, TBP, ERG, ASCL1, OGG1, MYC, SMARCA4, FOXP2, RAD21, GRHL3, GABPA, STAT3, APC, XRCC5, NR3C1, CEBPB, KMT2A, EZH2, GRHL2, SPI1, PCBP1, MYF5, RUNX1, SMC1A, EZH2phosphoT487, ZFX, TET2, NFXL1, CREBBP, ZNF384, TAF15, CDK6, ETV6, KDM6B, EVI1, FOXP1, AATF, SMC3, STAG1, TRP47, PPARG, AGO1, FOXA2, WT1, HOXB13, YY1, RELA, NEUROD1, SP140, ZIC2, HIF1A, OTX2, MAX, ZNF143, NCOA3, NR2F1, NEUROG2, TP53, MYOD1, AR, RXR, EGLN2, ZBTB42, HEXIM1, HSF1, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): POFUT2,FAM207A,COL18A1,ITGB2,PCBP3,ITGB2-AS1,SLC19A1,ADARB1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000160255,
ENSG00000227039,
ENSG00000160256,
ENSG00000197381,
ENSG00000186866,
ENSG00000182871,
ENSG00000173638,
ENSG00000183570,
- Related loop:
chr21:44925000-44950000~~chr21:45800000-45825000,
chr21:44950000-44975000~~chr21:45800000-45825000,
chr21:44975000-45000000~~chr21:45800000-45825000,
chr21:45125000-45150000~~chr21:45800000-45825000,
chr21:45150000-45175000~~chr21:45800000-45825000,
chr21:45200000-45225000~~chr21:45800000-45825000,
chr21:45275000-45300000~~chr21:45800000-45825000,
chr21:45300000-45325000~~chr21:45800000-45825000,
chr21:45325000-45350000~~chr21:45800000-45825000,
chr21:45350000-45375000~~chr21:45800000-45825000,
chr21:45425000-45450000~~chr21:45800000-45825000,
chr21:45450000-45475000~~chr21:45800000-45825000,
chr21:45525000-45550000~~chr21:45800000-45825000,
chr21:45550000-45575000~~chr21:45800000-45825000,
chr21:45575000-45600000~~chr21:45800000-45825000,
chr21:45675000-45700000~~chr21:45800000-45825000,