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Basic information

CohesinDB ID: CDBP00421359

Locus: chr21-45812475-45812693

Data sourse: GSE86191

Cell type: HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 83% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 64%, "14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: EZH2phosphoT487, TOP2A, ZFX, EZH2, SP140, ARNT, ZBTB48, WT1, FOXA1, HOXB13

Target gene symbol (double-evidenced CRMs): ITGB2,COL18A1,ADARB1,FAM207A,SLC19A1,POFUT2,PCBP3,ITGB2-AS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160255, ENSG00000227039, ENSG00000160256, ENSG00000197381, ENSG00000186866, ENSG00000182871, ENSG00000173638, ENSG00000183570,

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Deatailed information for cohesin site CDBP00421359