Deatailed information for cohesin site CDBP00421367

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  • Basic information
  • CohesinDB ID: CDBP00421367
  • Locus: chr21-45837172-45837882
  • Data sourse: ENCSR000BLD, GSE67783, ENCSR000BKV, GSE86191, GSE111913, ENCSR000BLY, GSE105028, GSE206145-NatGen2015, ENCSR000ECE, ENCSR000EHX, GSE83726, GSE145327, GSE97394
  • Cell type: H1-hESC, Fibroblast, HCT-116, RH4, HUES64, RT-112, SK-N-SH, K-562, HSPC, H9-hESC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 4% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.889
  • Subunit: SA1,Rad21,SA2,SMC1
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: TSS
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 83% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 54%, "7_Enh": 16%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: PGR, SOX2, XBP1, FOXA1, SUZ12, ZFHX2, HDGF, ZNF90, ATF3, THAP1, CTCFL, CHD7, CBFB, PAX5, TP63, MITF, MYOG, JMJD1C, ZNF506, ELF1, TEAD1, TRIM28, NFE2L2, LMO2, ESR1, MLL, USF2, CTCF, JUN, LMO1, E2F6, TRIM24, ZNF528, FOXA3, RBPJ, TFAP2C, GLIS1, JARID2, POU2F2, CHD8, BRD1, MYCN, ZNF263, POU5F1, ID3, CDK7, DUX4, ZSCAN5A, ZBTB48, DDX5, ERG2, ERG, ASCL1, OGG1, ZNF341, ETS1, MYC, SMARCA4, RFX1, RAD21, GRHL3, GABPA, STAT3, XRCC5, APC, PRDM14, RCOR1, DNMT3B, TERF2, ZNF639, ARNTL, NR3C1, CEBPB, SRSF3, KMT2A, CREB1, EZH2, GRHL2, EBF3, GABPB1, SPI1, ZNF257, KLF17, GATA2, MXD3, SIX2, FLI1, MXI1, ATF1, RUNX1, CBX1, SMC1A, CEBPA, NKX2-2, ZNF707, SIRT6, CRY1, ZFX, POU4F2, TET2, ERG3, ZNF770, TWIST1, RARA, ZNF384, NOTCH1, TAF15, RUNX2, ARNT, NRF1, PBX4, ZNF48, PRDM9, NCAPH2, FOS, CHD1, CDK8, KDM6B, MYB, SCRT2, ZNF3, KLF9, NCOA1, SETDB1, USF1, REST, TCF3, GLIS2, AATF, SMC3, STAG1, TRP47, ZNF283, CBFA2T2, FOXA2, AGO1, EBF1, CHD2, CREM, ZNF600, GTF2B, WT1, ZBTB33, CDK9, HOXB13, YY1, RELA, TARDBP, SP140, ZIC2, HIF1A, GATA3, TAL1, MAX, SPIB, ZNF143, HAND2, PLAG1, NCOA3, NR2F1, KDM5B, TP53, ZNF334, EGR2, T, BHLHE40, AR, RXR, ZBTB42, HEXIM1, TFIIIC, HSF1, NCOR1, BRD4, SCRT1, CLOCK, MAZ, AHR
  • Target gene symbol (double-evidenced CRMs): CFAP410,POFUT2,ADARB1,TRPM2,FAM207A,COL18A1,PCBP3,PFKL,SLC19A1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 8
  • Number of somatic mutations (non-coding): 8
  • Related genes and loops
  • Related gene: ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000160256, ENSG00000197381, ENSG00000186866, ENSG00000182871, ENSG00000173638, ENSG00000183570,
  • Related loop: chr21:44325000-44350000~~chr21:45825000-45850000, chr21:44950000-44975000~~chr21:45825000-45850000, chr21:44975000-45000000~~chr21:45825000-45850000, chr21:45125000-45150000~~chr21:45825000-45850000, chr21:45275000-45300000~~chr21:45825000-45850000, chr21:45425000-45450000~~chr21:45825000-45850000, chr21:45450000-45475000~~chr21:45825000-45850000, chr21:45550000-45575000~~chr21:45825000-45850000,
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