- Basic information
- CohesinDB ID: CDBP00421370
- Locus: chr21-45846697-45847005
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Data sourse: GSE206145-NatGen2015
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Cell type: Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 39%,
"7_Enh": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, SOX2, NME2, XBP1, FOXA1, SUZ12, HDGF, PRDM1, ZNF444, PAX5, ZSCAN4, MITF, CDX2, ELF1, ZNF573, ETV1, SNAI2, LMO2, ESR1, USF2, CTCF, EP300, BAF155, MNT, LMO1, DPF2, IRF4, RFX5, E2F1, TEAD4, RBPJ, TFAP2C, NANOG, ZNF263, MYCN, TOP2A, POU5F1, MTA2, ZBTB48, ERG, MYC, SMARCA4, RAD21, GRHL3, BATF3, GABPA, STAT3, NKX3-1, IKZF1, DNMT3B, NR3C1, CEBPB, CREB1, EZH2, GRHL2, SPI1, SSRP1, GATA2, SIX2, ZIM3, RUNX1, SMC1A, MAFG, EZH2phosphoT487, CRY1, SOX13, ZFX, ZNF18, ZNF384, NOTCH1, GR, ARNT, MED1, MYB, SCRT2, PIAS1, C11orf30, MAFK, HNF4A, ATF7, HNRNPLL, MLLT1, STAG1, PPARG, ZNF600, WT1, MAFF, MEF2C, CDK9, HOXB13, YY1, RELA, ZNF19, TARDBP, JUNB, SP140, HIF1A, GATA3, TAL1, MAX, ZNF143, CBX2, PLAG1, TCF7L2, NEUROG2, KDM5B, PKNOX1, ELF3, BHLHE40, AR, PAX3-FOXO1, EGLN2, IKZF2, BRD4, SCRT1, MAZ, ZNF316
- Target gene symbol (double-evidenced CRMs): ADARB1,COL18A1,CFAP410,PFKL,SLC19A1,PCBP3,FAM207A,TRPM2,POFUT2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000141959,
ENSG00000160226,
ENSG00000142185,
ENSG00000160256,
ENSG00000197381,
ENSG00000186866,
ENSG00000182871,
ENSG00000173638,
ENSG00000183570,
- Related loop:
chr21:44325000-44350000~~chr21:45825000-45850000,
chr21:44925000-44950000~~chr21:45850000-45875000,
chr21:44950000-44975000~~chr21:45825000-45850000,
chr21:44975000-45000000~~chr21:45825000-45850000,
chr21:45125000-45150000~~chr21:45825000-45850000,
chr21:45275000-45300000~~chr21:45825000-45850000,
chr21:45425000-45450000~~chr21:45825000-45850000,
chr21:45450000-45475000~~chr21:45825000-45850000,
chr21:45450000-45475000~~chr21:45850000-45875000,
chr21:45550000-45575000~~chr21:45825000-45850000,
chr21:45846155-45847509~~chr21:45879483-45881988,
chr21:45847135-45849106~~chr21:45879481-45881522,
chr21:45847135-45849106~~chr21:45922544-45924186,
chr21:45847189-45849001~~chr21:45879514-45881583,
chr21:45847196-45848957~~chr21:45879671-45881548,
chr21:45847206-45849095~~chr21:45879694-45881570,