- Basic information
- CohesinDB ID: CDBP00421376
- Locus: chr21-45856638-45858073
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Data sourse: GSE126634, GSE152721, GSE86191
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Cell type: HCT-116, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 49%,
"14_ReprPCWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: XBP1, FOXA1, SUZ12, ZFHX2, TFAP4, ATF3, PRDM1, MORC2, TP63, TRIM28, ESR1, OCA2, TP73, CTCF, JUN, GATA6, TEAD4, JARID2, POU2F2, CHD8, BRD1, MYCN, POU5F1, ZNF317, ZBTB48, STAT1, ERG2, ZNF300, ERG, ASCL1, OGG1, MYC, GRHL3, PROX1, APC, DNMT3B, CEBPB, EZH2, GRHL2, SPI1, HCFC1R1, RUNX1, CEBPA, EZH2phosphoT487, ZFX, POU4F2, TET2, ERG3, RUNX2, GATA4, ARNT, CHD1, FOS, REST, ZNF548, AATF, SMC3, STAG1, TRP47, ZNF316, ZNF600, MAFF, WT1, MEF2C, YY1, RELA, TARDBP, SP140, ZIC2, HIF1A, MAX, PLAG1, CEBPG, NCOA3, NEUROG2, NR2F1, TP53, ZNF334, EGR2, AR, ZNF366, HSF1, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): PCBP3,COL18A1,ITGB2,FAM207A,ITGB2-AS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 15
- Number of somatic mutations (non-coding): 3
- Related genes and loops