Browse_each

Basic information

CohesinDB ID: CDBP00421393

Locus: chr21-45917300-45917688

Data sourse: ENCSR703TNG, GSE206145-GSE177045, GSE67783, GSE86191

Cell type: MCF-7, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 83% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 57%, "14_ReprPCWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MBD3, FOXO1, NFIA, FOSL1, PGR, SMARCA2, NME2, PATZ1, FOXA1, SUZ12, PBX2, UBTF, ZNF28, ZFHX2, ATF3, NFIC, ZFP64, PRDM1, IKZF3, CBFB, ZNF273, MECOM, SMARCE1, TP63, MITF, TEAD1, ELF1, TRIM28, ETV1, KLF6, NFE2L2, ZNF217, ESR1, OCA2, LMO2, HDAC8, CTCF, TCF12, JUN, EP300, E4F1, PSIP1, ZBTB20, MNT, KLF1, DPF2, TRIM24, ZNF423, E2F1, NR5A2, GTF2F1, RBPJ, TFAP2C, GLIS1, JARID2, CHD8, BRD1, ZSCAN5D, MYCN, ZNF263, CDK7, POU5F1, CTBP1, ZBTB48, ZSCAN5A, STAT1, SRF, ZNF563, ERG2, HIC1, ZNF300, ERG, PBX1, OGG1, ZBTB8A, MYC, SMARCA4, RFX1, FOXP2, RAD21, GRHL3, STAT3, NKX3-1, PRDM14, IKZF1, RCOR1, DNMT3B, NFE2, ZNF667, NR3C1, CEBPB, ESRRA, KMT2A, CREB1, EZH2, BMPR1A, GRHL2, EBF3, ZHX2, SPI1, KLF17, PCBP1, HDAC2, GATA2, GATAD2B, FLI1, HCFC1R1, MRTFB, NCOA2, ZNF554, ATF1, RUNX1, CBX1, SMC1A, MAFG, SIRT6, BCL6, CEBPA, SIN3A, ZFX, TET2, ERG3, CBX8, TWIST1, PRDM10, SMARCC1, ZXDC, CREBBP, NOTCH1, RUNX2, GR, NFIB, ARNT, NRF1, ZBTB10, CHD1, FOS, MED1, ZEB1, KDM6B, ZNF680, SCRT2, ZNF3, NR1H2, KLF9, L3MBTL2, EVI1, USF1, NIPBL, TFAP2A, MAFK, BCL11A, REST, HNRNPLL, CTBP2, MBD2, GLIS2, TCF3, AATF, STAG1, TRP47, CBFA2T2, FOXA2, MTA3, EBF1, CHD2, SS18, HDAC6, ZNF600, ZSCAN16, ZNF692, WT1, YY1, RELA, BRG1, SP140, ZIC2, HIF1A, ZFP36, OTX2, GATA3, MAF1, MAX, NRIP1, ZNF143, GATA1, PLAG1, CBX2, KLF4, CEBPG, NCOA3, NR2F2, ZNF544, NR2F1, TCF7L2, KDM5B, TP53, ZBTB6, ZNF334, MYOD1, EGR2, BRD2, ELF3, AR, ZNF445, ZNF579, RXR, ZBTB42, HEXIM1, EGR1, HSF1, BRD4, SCRT1, JUND, MAZ, AHR

Target gene symbol (double-evidenced CRMs): ADARB1,SLC19A1,MCM3AP-AS1,COL6A2,PCBP3,DNMT3L,LSS

Function elements

Human SNPs: .

Number of somatic mutations (coding): 96

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000142182, ENSG00000197381, ENSG00000173638, ENSG00000183570, ENSG00000142173, ENSG00000160285, ENSG00000215424,

eachgene

Deatailed information for cohesin site CDBP00421393