- Basic information
- CohesinDB ID: CDBP00421407
- Locus: chr21-45959631-45960431
-
Data sourse: GSE67783, GSE86191, GSE110061, ENCSR153HNT, GSE116344
-
Cell type: K-562, RH4, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"14_ReprPCWk": 32%,
"15_Quies": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, PGR, XBP1, FOXA1, ZFHX2, TFAP4, ATF3, RUNX3, MECOM, TP63, ELF1, TEAD1, LMO2, ESR1, OCA2, CTCF, TCF12, JUN, E2F1, TFAP2C, EED, POU2F2, POU5F1, MYCN, RUNX1T1, KDM4C, ZNF263, ZBTB48, ERG2, ERG, MYC, SMARCA4, GRHL3, APC, STAT3, NKX3-1, ARNTL, NR3C1, CEBPB, CREB1, EZH2, BMPR1A, SPI1, FLI1, RUNX1, CRY1, ZFX, ZNF534, TET2, CBX8, SMARCC1, ZNF384, RUNX2, ARNT, ATF2, CDK8, MED1, TEAD3, NCOA1, SP1, BCL11A, REST, POU2F3, HNRNPLL, SMC3, STAG1, PPARG, TBL1X, EBF1, ZNF600, WT1, HOXB13, YY1, RELA, SP140, HIF1A, TAL1, ZNF143, NCOA3, NR2F2, NR2F1, PKNOX1, MYOD1, EGR2, AR, EGLN2, EGR1, HSF1, RNF2, BRD4, CLOCK, MAZ
- Target gene symbol (double-evidenced CRMs): LSS,COL6A2,FTCD,MCM3AP-AS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops