- Basic information
- CohesinDB ID: CDBP00421410
- Locus: chr21-45964738-45965740
-
Data sourse: GSE86191, GSE67783, GSE83726, ENCSR917QNE
-
Cell type: Liver, RH4, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 37%,
"9_Het": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: ZNF585B, TRIM28, ZFX, ZFP36, OTX2, SETDB1, MAZ, MYOD1, ZNF320, ZBTB7B
- Target gene symbol (double-evidenced CRMs): COL6A2,MCM3AP-AS1,FTCD,LSS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000142173,
ENSG00000160282,
ENSG00000160285,
ENSG00000215424,
- Related loop:
chr21:45950000-45975000~~chr21:46050000-46075000,
chr21:45950000-45975000~~chr21:46075000-46100000,
chr21:45950000-45975000~~chr21:46100000-46125000,
chr21:45950000-45975000~~chr21:46125000-46150000,
chr21:45950000-45975000~~chr21:46200000-46225000,
chr21:45969912-45971939~~chr21:46146852-46148242,
chr21:45969927-45971657~~chr21:46143028-46144654,
chr21:45969938-45971632~~chr21:46097212-46099767,