- Basic information
- CohesinDB ID: CDBP00421416
- Locus: chr21-46020986-46023884
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Data sourse: ENCSR230ZWH, ENCSR000BKV, GSE67783, GSE72082, GSE86191, GSE111913, GSE206145, GSE206145-NatGen2015, ENCSR054FKH, ENCSR153HNT, GSE83726
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Cell type: RPE, Fibroblast, HCT-116, RH4, Hep-G2, RT-112, K-562, Liver, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 29%,
"15_Quies": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, ZFX, STAG1
- Target gene symbol (double-evidenced CRMs): COL6A2
- Function elements
- Human SNPs: Intraocular_pressure
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 22
- Related genes and loops