Deatailed information for cohesin site CDBP00421418


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  • Basic information
  • CohesinDB ID: CDBP00421418
  • Locus: chr21-46027808-46029515
  • Data sourse: ENCSR000EFJ, ENCSR230ZWH, ENCSR917QNE, GSE206145-NatGen2015, ENCSR153HNT, GSE165895
  • Cell type: Fibroblast, IMR-90, K-562, Liver, HFFc6
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 4% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.944
  • Subunit: SA1,Rad21,SMC1,SA2,Mau2
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intergenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 84% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 39%, "9_Het": 17%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, PGR, FOXA2, ZSCAN5D, E2F7, CBX3, ZNF317, GTF2B, FOXA1, FOXF1, HOXB13, TWIST1, YY1, ZBTB21, RELA, ATF3, RUNX2, NFIC, GATA4, ZNF280A, ZNF184, RAD21, ARID1B, ARNT, ZIC2, NFIB, RXRA, HMGB2, ATF2, GABPA, ZNF189, STAT3, MAX, PBX3, ZNF518A, FOS, ZNF143, RCOR1, GATA1, HAND2, MED1, ZNF320, IKZF1, NR3C1, CEBPB, ZNF629, SP7, NR2F2, ZNF558, TRIM28, CREB1, PIAS1, ZNF791, EZH2, SMAD1, ZNF680, GRHL2, ZNF334, ZSCAN22, SETDB1, CTCF, TCF12, USF1, SP1, BAF155, ZNF577, HNF4A, AR, BHLHE40, GATA2, REST, ZNF324, TRIM24, SIX2, BRD4, JUND, E2F1, MAZ, ZNF350, ZNF528, TEAD4, ZNF554
  • Target gene symbol (double-evidenced CRMs): FTCD,COL6A2
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 16
  • Related genes and loops

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