- Basic information
- CohesinDB ID: CDBP00421419
- Locus: chr21-46031502-46031913
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Data sourse: GSE67783, ENCSR153HNT, GSE86191, GSE73207
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Cell type: K-562, TF-1, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 69%,
"14_ReprPCWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, TRIM25, HMG20A, E2F7, MEIS2, XBP1, FOXA1, HLF, PBX2, RXRB, ZFHX2, KDM3A, TFAP4, LYL1, ATF3, THRB, CTCFL, MXD4, TP63, MITF, ZNF629, KLF5, TEAD1, TRIM28, KLF6, RBM39, NFE2L2, ETV1, LMO2, ESR1, OCA2, RCOR2, USF2, CTCF, EP300, BAF155, MNT, GATA6, SOX5, E2F6, DMAP1, TRIM24, SOX6, E2F1, TEAD4, FOXA3, ZNF175, GATAD2A, RBPJ, EED, MLX, POU2F2, CHD8, BRD1, ZNF263, MYCN, RUNX1T1, ID3, TOP2A, CTBP1, POU5F1, ZBTB48, STAT1, NONO, GATAD1, SAP130, ERG2, ARID3A, HNF4G, ERG, MYC, SMARCA4, ARID1B, HOMEZ, RAD21, GRHL3, RXRA, GABPA, XRCC5, ZNF614, PRDM14, RCOR1, MIER3, NR2F6, NR3C1, ESRRA, CEBPB, HNRNPL, CREB1, ZBTB11, TBL1XR1, GRHL2, ZNF652, TRPS1, GABPB1, ZHX2, HES1, SPI1, TFE3, MIXL1, HDAC2, GATA2, SSRP1, MXD3, FLI1, DRAP1, ZGPAT, ZNF766, NFIL3, ZIM3, ATF1, ETV5, RUNX1, THAP11, BCL6, HDAC1, CEBPA, SOX13, ZFX, SIN3A, TET2, ERG3, SP5, SMARCC1, CREBBP, ZNF384, PRPF4, RARA, ARNT, ATF2, ZNF48, ZEB2, SMAD4, CBFA2T3, FOS, CDK8, HMGXB4, TEAD3, PML, DIDO1, MYB, PIAS1, ZNF3, L3MBTL2, MBD1, USF1, BCL11A, SP1, GSPT2, HNF4A, IKZF5, REST, ZNF479, ZBTB7A, ATF7, ASH2L, HNRNPLL, PHIP, FOXP1, AATF, STAG1, ETV4, SKI, TRP47, CBFA2T2, PPARG, CBX3, MTA3, CREM, FOXA2, ZNF600, FOXF1, ZBTB33, ZNF580, HOXB13, ZNF318, KDM1A, RELA, JUNB, NEUROD1, ZNF830, SP140, HIF1A, ZIC2, OTX2, GATA3, ZNF519, MGA, TAL1, MAX, MAF1, ZNF143, PLAG1, GFI1B, NR2F2, NR2F1, KDM5B, TP53, PKNOX1, ZBTB6, EGR2, ELF3, PHF5A, KAT8, BHLHE40, AR, PAX3-FOXO1, TAF1, ZBTB16, ZBTB40, ARID4B, NFKBIZ, HEXIM1, HSF1, RNF2, ZBTB26, JUND, BRD4, MAZ, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): FTCD,COL6A2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops