Deatailed information for cohesin site CDBP00421436


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  • Basic information
  • CohesinDB ID: CDBP00421436
  • Locus: chr21-46157182-46162882
  • Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE110061, GSE25021, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE131606, GSE165895
  • Cell type: MCF-7, RPE, Fibroblast, HCT-116, DKO, K-562, HSPC, HFFc6
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 3% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.911
  • Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: TSS,TES
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 84% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 34%, "15_Quies": 23%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: ZNF468, FOXO1, TRIM25, PGR, FOXA1, SUZ12, RBFOX2, LEO1, HNRNPK, ATF3, ZFP64, THAP1, KLF5, TEAD1, TRIM28, ESR1, USF2, CTCF, EP300, BAF155, TRIM24, E2F4, GTF2F1, RBPJ, GLIS1, BRD1, MYCN, ZNF263, POU5F1, ID3, ZBTB48, ERG, OGG1, ETS1, MYC, SMARCA4, RFX1, ZNF2, GRHL3, NKX2-1, GABPA, XRCC5, DNMT3B, NR3C1, SRSF3, HNRNPL, EZH2, GRHL2, GABPB1, ZHX2, ZNF202, ZNF257, PCBP1, SSRP1, RUNX1, SIRT6, FIP1L1, ZFX, ZNF534, SMAD3, PCBP2, ZNF770, ERG3, SMARCC1, PRDM10, PRPF4, ZNF384, TAF15, ZNF48, NCAPH2, FOS, SUPT5H, CHD1, TEAD3, ZEB1, ZNF3, SETDB1, RBM22, REST, ZBTB7A, HNRNPLL, TCF3, AATF, NFATC3, TRP47, FOXA2, AGO1, CBX3, CHD2, EBF1, ZNF600, WT1, ZNF30, ZBTB33, HOXB13, MPHOSPH8, KDM1A, YY1, RELA, TARDBP, ZNF148, NEUROD1, BRG1, SP140, KLF15, MAF1, MAX, AGO2, PLAG1, TP53, RUVBL1, ZNF334, AR, ZNF445, EGR1, TFIIIC, ZBTB26, BRD4, SCRT1, MAZ, AHR
  • Target gene symbol (double-evidenced CRMs): FTCD,SPATC1L
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 225
  • Number of somatic mutations (non-coding): 20
  • Related genes and loops

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