Deatailed information for cohesin site CDBP00421450


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  • Basic information
  • CohesinDB ID: CDBP00421450
  • Locus: chr21-46205119-46216728
  • Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, GSE116868, ENCSR760NPX, ENCSR000EGW, ENCSR000BLY, ENCSR150EFU, GSE105028, GSE121355, GSE131606, ENCSR330ELC, GSE108869, GSE25021, ENCSR000BUC, ENCSR917QNE, GSE115602, ENCSR000BTU, GSE93080, GSE143937, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE101921, GSE206145-NatGen2015, GSE120943, GSE130135, ENCSR199XBQ, ENCSR703TNG, ENCSR895JMI, ENCSR000EEG, ENCSR338DUC, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE206145, ENCSR000ECE, ENCSR247LSH, ENCSR981FDC, ENCSR000EHX, ENCSR620NWG, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, ENCSR217ELF, ENCSR000BTQ, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE110061, GSE129526, ENCSR676MJK, GSE111913, ENCSR335RKQ, ENCSR054FKH, ENCSR537EFT, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, ENCSR000ECS, ENCSR481YWD, GSE38411
  • Cell type: RH4, Liver, HuCC-T1, H9-hESC, RPE, Fibroblast, Ishikawa, HeLa-S3, K-562, BCBL-1, DKO, H1-hESC, Monocytes, MB157, GM12878, SK-N-SH, RT-112, MCF-7, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, A-549, HCAEC, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 29% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.722
  • Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: True
  • Genomic location: TSS,Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 84% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "4_Tx": 55%, "5_TxWk": 32%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: RUNX1, TRP47, PGR, FOXA2, MYCN, RBBP5, SIRT6, TOP2A, ZFX, ZNF600, ZNF263, AGO1, ZBTB48, WT1, PATZ1, FOXA1, ZSCAN5A, TET2, ERG3, ZBTB33, RBFOX2, LEO1, ERG2, ZFHX2, YY1, RELA, HDGF, PRPF4, PBX1, OGG1, TAF15, ATF3, MYC, ZNF384, THAP1, SP140, GRHL3, ZIC2, BACH1, PRDM9, SMAD4, GABPA, MAX, XRCC5, FOS, AGO2, SUPT5H, DNMT3B, HNRNPH1, PLAG1, NR3C1, ELF1, BCLAF1, KMT2A, RBM39, ZNF331, TFAP2C, TEAD1, ZNF3, TP53, ZNF334, USF2, SETDB1, EGR2, GABPB1, RBM22, AR, ZNF257, REST, ZNF605, BRD4, HNRNPLL, TCF3, MAZ, AATF, AHR
  • Target gene symbol (double-evidenced CRMs): COL6A2,LSS,FTCD,PCBP3
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 1068
  • Number of somatic mutations (non-coding): 146
  • Related genes and loops

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