- Basic information
- CohesinDB ID: CDBP00421481
- Locus: chr21-46282493-46283237
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Data sourse: GSE67783, GSE86191, ShirahigeLab, ShirahigeLab-NatGen2015, ENCSR153HNT, GSE25021
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Cell type: MCF-7, RPE, Fibroblast, HCT-116, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 33%,
"6_EnhG": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CEBPB, CEBPA, ZNF121, ZNF600, ZBTB48, PHIP, BCOR, ZNF770, DDX5, SUPT5H, MLLT1
- Target gene symbol (double-evidenced CRMs): YBEY
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000182362,
- Related loop:
chr21:46142465-46144615~~chr21:46285004-46287523,
chr21:46284828-46287850~~chr21:46324624-46326392,
chr21:46284891-46287117~~chr21:46325193-46327052,
chr21:46284913-46287579~~chr21:46323099-46326350,
chr21:46284994-46287562~~chr21:46323170-46326814,
chr21:46285004-46287523~~chr21:46324190-46326305,
chr21:46285202-46287572~~chr21:46324782-46326051,
chr21:46285204-46287304~~chr21:46324596-46326067,
chr21:46285206-46287083~~chr21:46324674-46326343,
chr21:46285212-46287543~~chr21:46321861-46326303,
chr21:46285216-46286892~~chr21:46324785-46326845,
chr21:46285222-46287087~~chr21:46324856-46327070,
chr21:46285272-46287549~~chr21:46324181-46326111,