Deatailed information for cohesin site CDBP00421495

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  • Basic information
  • CohesinDB ID: CDBP00421495
  • Locus: chr21-46321556-46327387
  • Data sourse: ENCSR230ZWH, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR917QNE, GSE115602, GSE93080, GSE67783, GSE86191, GSE101921, GSE120943, ENCSR198ZYJ, GSE130135, ENCSR199XBQ, GSE118494, ENCSR000EEG, ENCSR338DUC, ENCSR247LSH, GSE155324, ENCSR054FKH, GSE83726, GSE126755, ENCSR748MVX, ENCSR000ECS, GSE64758, ENCSR000BLD, GSE38411, GSE104888, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE106870, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR000BTQ, GSE129526, ENCSR537EFT, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE122299, GSE115250, GSE76893, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE38395, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE116868, ENCSR404BPV, GSE105028, ENCSR000EDW, GSE165895, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, ENCSR703TNG, GSE116344, GSE98367, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, GSE62063, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR153HNT, GSE68388, GSE126990
  • Cell type: MDM, RH4, GM10847, GM2610, CVB-hiPSC, GM19240, OCI-AML-3, HSPC, CVI-hiPSC, Liver, TC-32, HuCC-T1, B-cell, H9-hESC, GM2630, RPE, Fibroblast, HEKn, Ishikawa, GM12890, HeLa-S3, hLCL, GM2255, IMR-90, BCBL-1, K-562, GM18486, DKO, HFFc6, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, MB157, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, RT-112, GM19193, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, Ramos, HEK293T, Hep-G2, Neurons-H1, A-549, HCAEC, GM19238, Neutrophil, GM18951
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 53% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.300
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: True
  • Genomic location: TSS,TES
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 88% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "2_TssAFlnk": 30%, "1_TssA": 20%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: GLIS1, POU2F2, CEBPA, ZFX, ZNF600, XBP1, WT1, ZBTB48, DUX4, ZNF770, DDX5, ERG, RELA, ZNF384, THRB, MYC, OSR2, THAP1, SP140, PRDM9, ZEB2, GLYR1, GABPA, MAX, STAT3, ZNF143, DNMT3B, NR2F6, ZNF629, CEBPB, NCOA3, TEAD3, TFAP2C, SNAI2, OCA2, ZNF652, KLF1, PAX8, ZNF644, ZNF146, PRDM6, MAZ, AHR
  • Target gene symbol (double-evidenced CRMs): FTCD,C21orf58,YBEY,PCNT
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 174
  • Number of somatic mutations (non-coding): 116
  • Related genes and loops
  • Related gene: ENSG00000160282, ENSG00000182362, ENSG00000160298, ENSG00000160299,
  • Related loop: chr21:46146626-46148368~~chr21:46324586-46327028, chr21:46146642-46148386~~chr21:46324608-46326836, chr21:46284828-46287850~~chr21:46324624-46326392, chr21:46284891-46287117~~chr21:46325193-46327052, chr21:46284913-46287579~~chr21:46323099-46326350, chr21:46284994-46287562~~chr21:46323170-46326814, chr21:46285004-46287523~~chr21:46324190-46326305, chr21:46285202-46287572~~chr21:46324782-46326051, chr21:46285204-46287304~~chr21:46324596-46326067, chr21:46285206-46287083~~chr21:46324674-46326343, chr21:46285212-46287543~~chr21:46321861-46326303, chr21:46285216-46286892~~chr21:46324785-46326845, chr21:46285222-46287087~~chr21:46324856-46327070, chr21:46285272-46287549~~chr21:46324181-46326111,
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