- Basic information
- CohesinDB ID: CDBP00421496
- Locus: chr21-46327742-46329074
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Data sourse: GSE206145, GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 58%,
"5_TxWk": 39%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GLIS1, POU2F2, CEBPA, ZFX, ZNF600, XBP1, WT1, ZBTB48, DUX4, ZNF770, DDX5, ERG, RELA, ZNF384, THRB, MYC, OSR2, THAP1, SP140, PRDM9, ZEB2, GLYR1, GABPA, MAX, STAT3, ZNF143, DNMT3B, NR2F6, ZNF629, CEBPB, NCOA3, TEAD3, TFAP2C, SNAI2, OCA2, ZNF652, KLF1, PAX8, ZNF644, ZNF146, PRDM6, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): C21orf58,PCNT
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000160298,
ENSG00000160299,
- Related loop:
chr21:46146626-46148368~~chr21:46324586-46327028,
chr21:46146642-46148386~~chr21:46324608-46326836,
chr21:46284828-46287850~~chr21:46324624-46326392,
chr21:46284891-46287117~~chr21:46325193-46327052,
chr21:46284913-46287579~~chr21:46323099-46326350,
chr21:46284994-46287562~~chr21:46323170-46326814,
chr21:46285004-46287523~~chr21:46324190-46326305,
chr21:46285202-46287572~~chr21:46324782-46326051,
chr21:46285204-46287304~~chr21:46324596-46326067,
chr21:46285206-46287083~~chr21:46324674-46326343,
chr21:46285212-46287543~~chr21:46321861-46326303,
chr21:46285216-46286892~~chr21:46324785-46326845,
chr21:46285222-46287087~~chr21:46324856-46327070,
chr21:46285272-46287549~~chr21:46324181-46326111,