Deatailed information for cohesin site CDBP00421498


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  • Basic information
  • CohesinDB ID: CDBP00421498
  • Locus: chr21-46332516-46334205
  • Data sourse: ENCSR000EFJ, GSE67783, GSE86191, ENCSR000HPG, ENCSR000BLY, GSE111913, GSE206145-NatGen2015, ENCSR153HNT, GSE50893, GSE165895
  • Cell type: Fibroblast, HCT-116, GM18505, RT-112, IMR-90, SK-N-SH, K-562, HSPC, HFFc6
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 4% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.900
  • Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 88% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "5_TxWk": 56%, "4_Tx": 32%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: PGR, FOXA2, ZFX, ZBTB17, SMAD3, MEF2C, HOXC5, MEF2A, RELA, JUNB, ATF3, RUNX2, MYC, GATA4, RAD21, PBX4, DAXX, GATA3, GABPA, STAT3, MAX, PBX3, NKX3-1, FOS, CDK8, SUPT5H, RCOR1, ZNF143, MED1, NR3C1, CEBPB, CREB1, ESR1, MLL, HDAC8, ZNF334, NFKB1, JUN, TCF12, MAFK, SPI1, EP300, FLI1, MXI1, BRD4, JUND, ZNF528, MRTFB, PDX1, FOSL2
  • Target gene symbol (double-evidenced CRMs): PCNT
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 4
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000160299,
  • Related loop:

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