- Basic information
- CohesinDB ID: CDBP00421513
- Locus: chr21-46363641-46365053
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Data sourse: ENCSR000BLD, GSE67783, GSE86191, GSE111913, GSE105028, ENCSR153HNT, GSE68388, ENCSR703TNG
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Cell type: MCF-7, H1-hESC, HCT-116, RT-112, K-562, HSPC, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 76%,
"5_TxWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, FOSL1, SMC1A, BRD1, FOXA2, MYCN, ZNF263, POU5F1, SIN3A, ZFX, SIRT6, XBP1, ZBTB48, WT1, STAT1, TET2, ERG3, CDK9, ERG2, LEO1, ZFHX2, ERG, YY1, RELA, OGG1, ATF3, MYC, EZH1, RAD21, SP140, ARNT, GRHL3, CBFB, MECOM, STAT3, NCAPH2, TP63, SMARCB1, CDK8, AGO2, DNMT3B, PLAG1, KDM6B, TRIM28, CREB1, KDM5B, ZNF3, ESR1, TP53, LMO2, GRHL2, SETDB1, EGR2, CTCF, TCF12, RBM22, BCL11A, AR, RXR, REST, MXD3, HEXIM1, EGR1, TFIIIC, HSF1, PTBP1, BRD4, FOXP1, MAZ, AATF, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): PCNT
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 63
- Number of somatic mutations (non-coding): 0
- Related genes and loops