- Basic information
- CohesinDB ID: CDBP00421517
- Locus: chr21-46375589-46377385
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Data sourse: GSE67783, GSE86191, GSE206145-NatGen2015, ENCSR153HNT, GSE131606
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Cell type: Fibroblast, HCT-116, K-562, HSPC, DKO
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 57%,
"4_Tx": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SOX2, ZNF101, LEO1, ATF3, CBFB, TP63, ELF1, TRIM28, ESR1, CTCF, JUN, KLF1, PAX8, PDX1, TFAP2C, POU5F1, MYCN, TOP2A, ZNF263, DUX4, ZBTB48, ZSCAN5A, ERG, OGG1, MYC, SMARCA4, GRHL3, GABPA, STAT3, DNMT3B, NR3C1, EZH2, MXD3, SIX2, FLI1, HCFC1R1, NFYB, RUNX1, SMC1A, NKX2-2, SIRT6, ZFX, TET2, ERG3, ZNF384, ARNT, ZNF48, NCAPH2, SMARCB1, TERF1, SCRT2, ZNF41, ZNF22, RBM22, BCL11A, HNRNPLL, AATF, SMC3, STAG1, TRP47, CBFA2T2, AGO1, FOXA2, ZNF600, WT1, YY1, RELA, NEUROD1, SP140, ZIC2, OTX2, TAL1, AGO2, NR2F1, KDM5B, TP53, MYOD1, RBM14, AR, RXR, HEXIM1, TFIIIC, HSF1, SCRT1, BRD4, MAZ
- Target gene symbol (double-evidenced CRMs): PCNT
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops