Deatailed information for cohesin site CDBP00421535


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  • Basic information
  • CohesinDB ID: CDBP00421535
  • Locus: chr21-46413887-46415371
  • Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR153HNT, GSE86191
  • Cell type: K-562, Fibroblast, HCT-116, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.956
  • Subunit: SA1,Rad21,SA2
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 88% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "4_Tx": 49%, "5_TxWk": 47%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: TRIM25, FOSL1, PGR, HMGN3, XBP1, FOXA1, LEO1, ZFHX2, HDGF, ATF3, ZNF362, CTCFL, KLF14, CBFB, TP63, TEAD1, TRIM28, ELF1, SNAI2, ESR1, USF2, CTCF, ZNF528, TEAD4, TFAP2C, JARID2, CHD8, BRD1, ZSCAN5D, ZNF263, MYCN, POU5F1, RUNX1T1, ZBTB48, ZSCAN5A, ERG2, SP4, ERG, OGG1, ETS1, MYC, GRHL3, GABPA, STAT3, DNMT3B, NR3C1, CEBPB, HNRNPL, EZH2, ZHX2, FLI1, RUNX1, SMC1A, NKX2-2, SIRT6, ZFX, NFKBIA, ERG3, NFXL1, RARA, ZNF384, GR, SP3, ARNT, PRDM9, SATB1, NCAPH2, SUPT5H, ZNF3, KLF9, ZNF22, RBM22, SP1, TFAP2A, REST, CTBP2, MBD2, AATF, SMC3, STAG1, TRP47, AGO1, FOXA2, RBBP5, TBL1X, ZNF600, WT1, ZBTB33, YY1, RELA, TARDBP, SP140, ZIC2, HIF1A, KLF15, TAL1, MAX, ZNF143, AGO2, NCOA3, NR2F1, KDM5B, TP53, ZNF334, EGR2, ARRB1, AR, RXR, HEXIM1, EGR1, TFIIIC, HSF1, BRD4, SCRT1, CLOCK, MAZ
  • Target gene symbol (double-evidenced CRMs): PCNT
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 20
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000160299,
  • Related loop:

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