Deatailed information for cohesin site CDBP00421592


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  • Basic information
  • CohesinDB ID: CDBP00421592
  • Locus: chr21-46545292-46547043
  • Data sourse: GSE67783, GSE86191, GSE111913, ShirahigeLab, GSE85526, ENCSR153HNT, GSE25021
  • Cell type: MCF-7, RPE, HCT-116, HEKn, RT-112, K-562, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 3% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.922
  • Subunit: SA1,Rad21,SA2,SMC1
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 86% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "4_Tx": 69%, "5_TxWk": 15%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: RUNX1, TRP47, POU2F2, SMC1A, PGR, CBX1, ZNF263, MYCN, FOSL1, ZSCAN5D, ZFX, CBFA2T2, EBF1, BRD1, ZBTB48, WT1, ZSCAN5A, FOXA1, XBP1, TET2, ERG3, TBL1X, ERG2, ZFHX2, NSD2, YY1, RELA, CREBBP, ATF3, MYC, AHR, SP140, ARNT, HIF1A, NRF1, GRHL3, MAX, TP63, FOS, ZNF143, CHD1, DNMT3B, AGO2, MED1, SMARCB1, TEAD1, NR2F1, ZNF3, ESR1, OCA2, TP53, KLF9, GRHL2, ZNF334, CHD8, TRIM25, EGR2, CTCF, RBM22, MAFK, RBM14, MNT, SSRP1, REST, EGLN2, HEXIM1, HSF1, HNRNPLL, BRD4, MAZ, AATF, SMC3, STAG1, TFAP2C
  • Target gene symbol (double-evidenced CRMs): DIP2A
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 250
  • Number of somatic mutations (non-coding): 50
  • Related genes and loops

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