- Basic information
- CohesinDB ID: CDBP00421593
- Locus: chr21-46547707-46548449
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Data sourse: GSE67783, GSE86191, GSE98367, ShirahigeLab, ShirahigeLab-NatGen2015, GSE120943, ENCSR153HNT
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Cell type: RPE, Fibroblast, HCT-116, Monocytes, K-562, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 65%,
"5_TxWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MYCN, TOP2A, MEIS1, ZFX, NME2, ZNF317, ZBTB48, ZSCAN5A, WT1, LEO1, YY1, HDGF, ZNF384, TARDBP, ZNF341, EHMT2, MYC, SP140, PRDM1, TAL1, ETV6, PBX3, SUPT5H, CDK8, CDX2, TRIM28, TP53, ESR1, NCOR2, ZNF22, CTCF, RBM22, AR, TCF3, MAZ, ZNF280A, ZFP82, STAG1
- Target gene symbol (double-evidenced CRMs): DIP2A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 30
- Number of somatic mutations (non-coding): 10
- Related genes and loops