Deatailed information for cohesin site CDBP00421595


Check detailed explainations here

  • Basic information
  • CohesinDB ID: CDBP00421595
  • Locus: chr21-46550355-46552742
  • Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, GSE105028, GSE103477, GSE25021, ENCSR917QNE, GSE67783, GSE86191, GSE206145-NatGen2015, GSE120943, GSE106870, GSE98367, ENCSR000ECE, ENCSR000BTQ, ENCSR167MTG, GSE111913, GSE155324, ENCSR153HNT, GSE50893, GSE126755, GSE131577
  • Cell type: MDM, GM10847, GM2610, HSPC, CVI-hiPSC, Liver, H9-hESC, GM2630, Fibroblast, GM2255, K-562, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, Lymphoblast, GM12878, GM12891, GM2588, GM19239, RT-112, GM19193, THP-1, Macrophage, MCF-7, GM12892, HCT-116, HL-60, Hep-G2, GM19238, Neutrophil, GM18951
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 13% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.633
  • Subunit: SA1,Rad21,SMC1,SA2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 86% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "4_Tx": 40%, "5_TxWk": 20%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: RUNX1, TRP47, CBFA2T2, BCL6, SMC1A, FOXA2, MYCN, ZSCAN5D, CEBPA, PAF1, ZFX, ZNF263, XBP1, EBF1, ZBTB48, WT1, FOXA1, LEO1, ERG, YY1, RELA, RARA, CREBBP, OGG1, ZNF341, ATF3, MYC, RUNX2, SMARCA4, RUNX3, SP140, GRHL3, CBFB, ZNF48, GATA3, GABPA, STAT3, TAL1, NKX3-1, FOS, GATA1, NFE2, AGO2, CHD1, DNMT3B, MED1, NR3C1, CEBPB, PDX1, MAF, STAT5B, KDM6B, KMT2A, MYB, KDM5B, STAG1, EZH2, OCA2, KLF9, ZNF334, USF2, CTCF, RBM22, JUN, BCL11A, SPI1, TBX21, LMO1, AR, BHLHE40, DPF2, HSF1, BRD4, TCF3, MAZ, MLLT1
  • Target gene symbol (double-evidenced CRMs): PRMT2,DIP2A
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 164
  • Number of somatic mutations (non-coding): 82
  • Related genes and loops

eachgene