Deatailed information for cohesin site CDBP00421598


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  • Basic information
  • CohesinDB ID: CDBP00421598
  • Locus: chr21-46556860-46558540
  • Data sourse: ENCSR000BLD, GSE67783, GSE86191, GSE111913, ShirahigeLab, ENCSR153HNT
  • Cell type: RPE, H1-hESC, HCT-116, RT-112, K-562, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 2% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.933
  • Subunit: SA1,Rad21
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 86% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "4_Tx": 55%, "5_TxWk": 27%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXA1, LEO1, ZFHX2, ATF3, THAP1, CTCFL, CBFB, TP63, TRIM28, RBM39, ESR1, CTCF, GATA6, CHD8, BRD1, MYCN, ZNF263, ZBTB48, ZSCAN5A, ERG2, ERG, OGG1, MYC, GRHL3, STAT3, DNMT3B, HNRNPH1, SRSF3, HNRNPL, GRHL2, GABPB1, ETV5, PTBP1, RUNX1, SMC1A, SIN3A, ZFX, ERG3, CREBBP, RARA, NOTCH1, TAF15, ZNF48, NCAPH2, CHD1, SUPT5H, FOS, SMARCB1, MYB, ZNF3, RBM22, ZBTB7A, HNRNPLL, TCF3, AATF, SMC3, STAG1, TRP47, FOXA2, ZNF600, WT1, ZBTB33, RELA, TARDBP, SP140, HIF1A, TAL1, MAX, AGO2, PLAG1, NR2F1, KDM5B, TP53, MYOD1, EGR2, AR, RXR, HEXIM1, EGR1, TFIIIC, HSF1, BRD4, CLOCK, MAZ, AHR
  • Target gene symbol (double-evidenced CRMs): DIP2A
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 264
  • Number of somatic mutations (non-coding): 132
  • Related genes and loops

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