- Basic information
- CohesinDB ID: CDBP00421614
- Locus: chr21-46603124-46603599
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Data sourse: ENCSR000BLD, ENCSR000BTU, GSE138405, GSE25021, GSE105028, ENCSR703TNG, GSE106870
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Cell type: MCF-7, H1-hESC, Hela-Kyoto, Hep-G2, CVB-hiPSC, Ishikawa, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 37%,
"5_TxWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, TRIM25, PGR, SMARCA2, SOX2, MEIS2, FOXA1, HLF, SUZ12, PBX2, ZFHX2, TFAP4, HDGF, LYL1, ATF3, CHD7, PRDM1, RUNX3, CBFB, ZNF189, MECOM, PAX5, TP63, MITF, JMJD1C, INTS11, MAF, TEAD1, TRIM28, ELF1, RBM39, BCLAF1, NFE2L2, LMO2, ESR1, MLL, OCA2, PITX3, CTCF, TCF12, KLF1, ARID5B, LMO1, PAX8, DPF2, E2F6, TRIM24, IRF4, TEAD4, KMT2B, PDX1, TFAP2C, RBPJ, EED, CHD8, BRD1, ZNF263, MYCN, POU5F1, ID3, RUNX1T1, CDK7, ZBTB17, ZBTB48, STAT1, MLLT3, ERG2, SP4, ERG, OGG1, ZBTB8A, ONECUT1, MYC, SMARCA4, EZH1, RAD21, GRHL3, GABPA, STAT3, XRCC5, IKZF1, NFE2, TERF2, VDR, NR3C1, CEBPB, HNRNPL, STAT5B, KMT2A, EZH2, BMPR1A, ZNF652, SPI1, GATA2, INTS13, GATAD2B, FLI1, SMARCA5, HCFC1R1, NCOA2, RUNX1, BCL6, SMC1A, CEBPA, NKX2-2, SIRT6, ZFX, TET2, CBX8, ERG3, SMARCC1, PRDM10, TWIST1, RARA, ZNF384, NFYC, RUNX2, ARNT, FOXM1, MAFB, SP2, CDK8, MED1, TEAD3, TERF1, KDM6B, MYB, ZNF680, SCRT2, VEZF1, ZNF3, KLF9, C11orf30, EVI1, STAT5A, MAFK, SP1, BCL11A, GSPT2, NR4A1, ZSCAN31, ASH2L, HNRNPLL, PHIP, TCF3, AATF, SMC3, STAG1, MLLT1, SKI, TRP47, FOXA2, AGO1, EBF1, CHD2, MEIS1, ZNF600, ZNF692, WT1, MEF2C, CDK9, HOXB13, KDM1A, YY1, RELA, TARDBP, NEUROD1, SP140, ZFP36, ZIC2, PCGF1, TCF4, OTX2, GATA3, BHLHE22, TAL1, ZNF740, MAX, SPIB, ZNF143, HAND2, CBX2, CEBPG, BCL11B, GFI1B, KDM5B, TP53, PKNOX1, MED, ZNF334, MYOD1, EGR2, BRD2, TBX21, AR, PAX3-FOXO1, ZBTB16, ZBTB42, EGR1, HEXIM1, RB1, ZBTB26, MYNN, RNF2, BRD4, HSF1, IKZF2, CLOCK, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): S100B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 14
- Number of somatic mutations (non-coding): 7
- Related genes and loops