- Basic information
- CohesinDB ID: CDBP00421616
- Locus: chr21-46608490-46609538
-
Data sourse: GSE93080, ENCSR000EAC, ENCSR000DZP, ENCSR000BMY, GSE50893
-
Cell type: GM12892, GM18526, GM2630, SNYDER, GM2610, GM19240, GM12878, GM12891, GM2588, GM12890, GM19238, GM19099, GM2255, GM19239, GM18486
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.833
- Subunit: SMC3,Rad21,SA1,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 58%,
"14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: POU2F2, SMC1A, FOXA2, ZNF600, MTA2, GTF2B, DUX4, XBP1, FOXA1, CBX8, SUZ12, NBN, TRIM22, ERG, YY1, RELA, ZBTB2, CHD4, JUNB, MYC, NFIC, GATA4, RUNX3, RAD21, GRHL3, PRDM9, BATF, TAL1, PAX5, CBFA2T3, STAT3, SPIB, IKZF1, ZNF143, KLF5, PML, BCLAF1, TRIM28, MYB, EZH2, PKNOX1, OCA2, ZNF334, SETDB1, CTCF, TCF12, SPI1, BCL11A, TBX21, BHLHE40, AR, ZNF157, TAF1, DPF2, SP1, GATA2, HDAC2, IRF4, ATF7, ASH2L, IKZF2, JUND, SMARCA5, BRD4, RELB, MLLT1, RBPJ, EED
- Target gene symbol (double-evidenced CRMs): S100B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 8
- Related genes and loops