- Basic information
- CohesinDB ID: CDBP00421629
- Locus: chr21-46644903-46645378
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Data sourse: ENCSR000BLD, ENCSR000BTU, GSE72082, ENCSR000BKV, GSE86191, ENCSR000BSB, GSE138405, GSE110061, GSE129526, GSE111913, ENCSR000BLY, GSE25021, ENCSR000BLS, GSE105028, GSE152721, ENCSR000ECE, GSE111537, GSE126990, GSE97394
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Cell type: H1-hESC, Hela-Kyoto, HCT-116, Hep-G2, Ishikawa, HUES64, RT-112, SK-N-SH, K-562, OCI-AML-3, HAP1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.867
- Subunit: SMC3,Rad21,SA2,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 85%,
"5_TxWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GLIS1, POU2F2, CHD8, BCL6, ZSCAN5D, MYCN, POU5F1, SIRT6, PAF1, ZFX, ZNF600, NME2, ZNF263, ZBTB48, WT1, SMAD3, FOXA1, XBP1, ZNF770, ZBTB33, RBFOX2, LEO1, HOXB13, PRDM10, ERG, YY1, RELA, ZNF384, JUNB, INSM2, MYC, GATA4, ZNF362, RAD21, SP140, ZIC2, ARNT, GRHL3, NKX2-1, ATF2, GATA3, CBFB, ZNF189, STAT3, GABPA, TOP2A, SUPT5H, AGO2, FOS, ZNF143, KLF4, ZNF629, CEBPB, NR3C1, TEAD1, SCRT2, SNAI2, TFAP2C, EZH2, ESR1, OCA2, GRHL2, JUN, CTCF, RBM22, BCL11A, AR, FOXA2, ZBTB40, GATA2, EGLN2, TRIM24, CEBPA, JUND, BRD4, FOXP1, MAZ, SMC3, STAG1, AHR, EED
- Target gene symbol (double-evidenced CRMs): PRMT2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 40
- Number of somatic mutations (non-coding): 4
- Related genes and loops