- Basic information
- CohesinDB ID: CDBP00421630
- Locus: chr21-46645871-46647210
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Data sourse: GSE67783, GSE86191, GSE126634, GSE111913, GSE152721, ENCSR153HNT
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Cell type: HCT-116, RT-112, HSPC, K-562, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 71%,
"5_TxWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PAX7, PGR, FOXA2, MYCN, ZNF263, TOP2A, ZFX, ZNF600, XBP1, GTF2B, ZBTB48, WT1, DUX4, FOXA1, ZNF770, ERG3, ZBTB33, ERG2, HOXB13, SMARCC1, PRDM10, YY1, ETS1, MYC, AHR, TSHZ1, OSR2, PRDM1, ZIC2, ARNT, HIF1A, SOX11, NKX2-1, GATA3, STAT3, PAX5, ZNF10, SP7, ZEB1, TEAD1, ZXDB, TRIM28, TCF7L2, KDM5B, ESR1, TP73, ZFP42, CTCF, EP300, AR, PAX3-FOXO1, E2F6, ZNF644, ZNF182, FLI1, PRDM6, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): PRMT2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 20
- Number of somatic mutations (non-coding): 2
- Related genes and loops