- Basic information
- CohesinDB ID: CDBP00421635
- Locus: chr21-46658601-46659062
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 65%,
"5_TxWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PAX7, CBX5, CHD8, POU2F2, CBX3, MYCN, EBF1, ZNF263, PAF1, ZFX, ZNF600, XBP1, RBBP5, DUX4, WT1, ZSCAN5A, FOXA1, SIN3A, ZBTB48, ERG3, TBL1X, MAFF, LEO1, HOXB13, ZFHX2, MPHOSPH8, ZNF300, RELA, ZNF90, JUNB, MYC, SP140, ARNT, POU5F1, GTF2B, MAFB, NKX3-1, SUPT5H, AGO2, RCOR1, CRY1, ZNF143, FOS, MAF, PDX1, TRIM28, ZNF3, ESR1, OCA2, NCOA1, HDAC8, SETDB1, MYOD1, EGR2, CTCF, RBM22, MAFK, SPI1, AR, FOXA2, PAX8, E2F6, TRIM24, ZNF146, FLI1, BRD4, AFF1, NKX2-2, MAZ, ZNF280A, SMC3, ZNF92, STAG1, ZNF316
- Target gene symbol (double-evidenced CRMs): PRMT2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 216
- Number of somatic mutations (non-coding): 27
- Related genes and loops